Description
FTO, His-tag (Sf9 derived) Recombinant
| Catalog number: | B2019118 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 g |
| Molecular Weight or Concentration: | 56 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 80C |
| Keywords: | Fat mass and obesity-associated protein, ALKBH9, BMIQ14, GDFD, KIAA1752, alpha-ketoglutarate-dependent dioxygenase, fto |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Liu S, Xiu J, Zhu C, Meng K, Li C, Han R, Du T, Li L, Xu L, Liu R, Zhu W, Shen Y, Xu Q. Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice Nat Commun. 2021 Nov 26;12(1):6937.
- Wu Y, Li J, Li C, Lu S, Wei X, Li Y, Xia W, Qian C, Wang Z, Liu M, Gu Y, Huang B, Tan Y, Hu Z. Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner J Biol Chem. 2023 Jun;299(6):104783.
- Song Y, Wade H, Zhang B, Xu W, Wu R, Li S, Su Q. Polymorphisms of Fat Mass and Obesity-Associated Gene in the Pathogenesis of Child and Adolescent Metabolic Syndrome Nutrients. 2023 Jun 6;15(12):2643.
- Wei X, Zhang J, Tang M, Wang X, Fan N, Peng Y. Fat mass and obesity-associated protein promotes liver steatosis by targeting PPAR Lipids Health Dis. 2022 Mar 13;21(1):29.
- Zhang C, Guan G, Wang J, Wei H, Cai J. MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury Ren Fail. 2023;45(2):2285869.
- Azzam SK, Alsafar H, Sajini AA. FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms Int J Mol Sci. 2022 Mar 30;23(7):3800.
- Shan HJ, Gu WX, Duan G, Chen HL. Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krppel-like factor 3 (KLF3) promotes osteosarcoma progression Bioengineered. 2022 Apr;13(4):8038-8050.
- Li Y, Su R, Deng X, Chen Y, Chen J. FTO in cancer: functions, molecular mechanisms, and therapeutic implications Trends Cancer. 2022 Jul;8(7):598-614.
- Masoud Abd El Gayed E, Kamal El Din Zewain S, Ragheb A, ElNaidany SS. Fat mass and obesity-associated gene expression and disease severity in type 2 diabetes mellitus Steroids. 2021 Oct;174:108897.
