Description
Histidine Buffer (0.2 M, pH 7.0)
| Catalog number: | B2017977 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 mL |
| Molecular Weight or Concentration: | 0.2 M |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8 |
| Keywords: | N/A |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Holeek M. Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement Nutrients. 2020 Mar 22;12(3):848.
- Doyle Drbohlav LM, Sharma AN, Gopalrathnam G, Huang L, Bradley S. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems-Part 2 PDA J Pharm Sci Technol. 2019 Jul-Aug;73(4):320-330.
- Berenbrink M. Evolution of vertebrate haemoglobins: Histidine side chains, specific buffer value and Bohr effect Respir Physiol Neurobiol. 2006 Nov;154(1-2):165-84.
- Zhang Y, Schneich C. Near UV light photo-degradation of histidine buffer: Mechanisms and role of Fe(III) Eur J Pharm Biopharm. 2023 Sep;190:231-241.
- Lei M, Quan C, Wang YJ, Kao YH, Schneich C. Light-Induced Covalent Buffer Adducts to Histidine in a Model Protein Pharm Res. 2018 Feb 20;35(3):67.
- Kolhe P, Amend E, Singh SK. Impact of freezing on pH of buffered solutions and consequences for monoclonal antibody aggregation Biotechnol Prog. 2010 May-Jun;26(3):727-33.
- Brov EV, Mravljak J, ink R, Pajk S. Degradation of polysorbates 20 and 80 catalysed by histidine chloride buffer Eur J Pharm Biopharm. 2020 Sep;154:236-245.
- Zhang Y, Ballesteros ME, Schneich C. Photo-induced site-specific oxidative fragmentation of IgG1 mediated by iron(III)-containing histidine buffer: Mechanistic studies and excipient effects Eur J Pharm Biopharm. 2023 Sep;190:121-130.
- Zhang Y, Schneich C. Visible Light Induces Site-Specific Oxidative Heavy Chain Fragmentation of a Monoclonal Antibody (IgG1) Mediated by an Iron(III)-Containing Histidine Buffer Mol Pharm. 2023 Jan 2;20(1):650-662.









